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KMID : 1123920040180051512
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Korean Journal of Oriental Physiology and Pathology
2004 Volume.18 No. 5 p.1512 ~ p.1515
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Comparative Study of Nitric Oxide Scavenging Effect in Several Herbal Extracts
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Yoo Yeong-Min
Lee Seon-Goo
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Abstract
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In this study, we investigated in vitro nitric oxide (NO) scavenging effect on nine herbal extracts using an NO donor S-nitroso-N-acetylpenicillamine (SNAP) compared with vitamin C. All herbal extracts effectively reduced the generation of NO radicals in a dose-dependant manner and over 65% in 10h. Especially, Ephedrae herba, Carthami flos and Lonicerae flos declined over 75% of NO scavenging effect, suggested that the herbal extracts are the powerful free radical scavengers and may be effective in clinical applications.
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KEYWORD
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nitric oxide, S-nitroso-N-acetylpenicillamine, Griess reagent, antioxidant
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